Hemolytic and cytotoxic effects of saponin like compounds isolated from Persian Gulf brittle star ( Ophiocoma erinaceus )
نویسندگان
چکیده
Hemolytic and cytotoxic effects of saponin like compounds isolated from Persian Gulf brittle star (Ophiocoma erinaceus) Elaheh Amini*, Mohammad Nabiuni, Javad Baharara, Kazem Parivar, Javad Asili Developmental Biology, Kharazmi University, Tehran, Iran Biology, Research Center For Applied Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran Cell and Developmental Biology, Science and Research Branch Tehran Islamic Azad University, Tehran, Iran Department of Pharmacogenosy, Faculty of Pharmacology, Mashhad University of Medical Sciences, Mashhad, Iran Journal of Coastal Life Medicine 2014; 2(10): 762-768
منابع مشابه
Anti-inflammatory properties of saponin fraction from (Spiny brittle star) Ophiocoma erinaceus (Müller and Troschel, 1842)
Marine saponins are naturally glycosides compounds which possess important biomedical properties such as anti-cancer, antioxidant and anti-inflammatory. Nevertheless, no systematic studies on the anti-inflammatory potential of brittle star saponin and its underlying mechanisms have been reported. In this study, Ophiocoma erinaceus extracted saponin was investigated for its in vitro anti-inflamm...
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Background: Brittle stars can produce well-known toxins responsible for various of their biological activities in addition to their physical defense. The purpose of this study was to identify secondary metabolites and assess the anticholinesterase activities of the crude venom of the Persian Gulf Ophiocoma erinaceous (brittle star) in vitro and in silico due to the abundance of this marine life...
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Background and Objective: The natural products are considered promising candidates for cancer treatment. Brittle stars are echinoderms that biologically include active compounds. The aim of this study was to evaluate the effect of the Persian Gulf brittle star (Ophiocoma erinaceus) dichloromethane extract on induction of apoptosis in the EL4 cell line. Materials and Methods: In this...
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Ophiocoma erinaceus Muller &Troschel (Ophiocomidae) is part of the extensive group of echinoderm that contains bioactive metabolites. As, the anti cancer potential of brittle star saponin has not been reported against cervical cancer, the present study was conducted to evaluate the anticancer effect of extracted crude saponin. Saponin extraction was conducted using conventional method such as f...
متن کاملIn vitro pro apoptotic effect of crude saponin from Ophiocoma erinaceus against cervical cancer
Ophiocoma erinaceus Muller &Troschel (Ophiocomidae) is part of the extensive group of echinoderm that contains bioactive metabolites. As, the anti cancer potential of brittle star saponin has not been reported against cervical cancer, the present study was conducted to evaluate the anticancer effect of extracted crude saponin. Saponin extraction was conducted using conventional method such as f...
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